MEGABASE is a neural network that generates chromatin compartment and sub-compartment annotations from epigenetic information.

MEGABASE uses Chromatin Immunoprecipitation (ChIP-Seq) data to predict the most likely sequence of chromatin structural types for any given chromosomes. This sequence of chromatin types is used as input for the Minimal Chromatin Model, allowing for the study of the structure and dynamics of genomic material.